Get the best 49ers vs. Colts predictions and odds ahead of Week 16 Monday Night Football on December 22, 2025. Take the Over.

The Denver Broncos and Kansas City Chiefs are facing off in the finale of today’s Christmas Day NFL games. The Broncos lead 13-10 in the fourth quarter. Follow for play-by-play updates and analysis of tonight's game. Share your thoughts with us at [email protected] and check out our live schedule here.