Cancer has long been treated as a mass of rogue cells, but the real power lies in the intricate communication networks ...

This important study provides a detailed analysis of the transcriptional landscape of the mouse hippocampus in the context of various physiological states. The main conclusions have solid support: ...

Researchers have shown that glioblastoma can take over the skull marrow to dissolve bone and feed its own growth, suggesting ...

AI therapeutics company built on causal biology, today announced the publication of research in Nature Communications validating its POSH (Pooled Optical Screening in Human cells) platform. The study ...

Researchers developed and validated a non-invasive urinary microRNA aging clock using extracellular vesicle miRNAs from more ...

Background Western diet and associated production of secondary bile acids (BAs) have been linked to the development of ...

The pipeline's workflow begins with the essential step of quality assessment. All incoming raw sequencing read files (typically in .fastq format) are first processed by FastQC. This tool generates ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

RNA sequencing (RNA-Seq) is a high-throughput sequencing approach that enables comprehensive quantification of transcriptomes at a genome-wide scale. As a result, RNA-Seq has become a routine ...

Abstract: An average person usually contains more than 10 trillion human cells, and each cell's transcriptome can be profiled by a single-cell RNA sequence (scRNA-seq). The huge volume and high ...