Pepsin is an aspartic protease, using a catalytic aspartate in its active site. [2] It is one of three principal endopeptidases (enzymes cutting proteins in the middle) in the human digestive …

Nov 5, 2018 · The definition of pepsin is a digestive enzyme in the stomach that breaks down proteins into smaller units called polypeptides (or peptides for short). This enzyme helps digest …

Pepsin is a powerful enzyme in gastric juice that digests proteins such as those in meat, seeds, and dairy products. It is the mature active form of pepsinogen, which is released into the …

May 1, 2023 · Pepsin is an endopeptidase that breaks down dietary proteins reaching the stomach into amino acids. It functions by digesting peptide bonds, the predominant chemical …

Aug 6, 2025 · How Pepsin Works Pepsin’s function is to break down large protein molecules into smaller units called polypeptides. This initial breakdown is a step in protein digestion. Pepsin …

Feb 24, 2025 · At-A-Glance The digestive enzyme pepsin, not acid, is the primary culprit behind reflux-related damage. Unlike acid, pepsin sticks to tissues in the throat and airways, …

Nov 7, 2025 · Pepsin is the primary protein-digesting enzyme in the stomach, responsible for breaking down dietary proteins into smaller peptides that can be further processed by …

Pepsin is a digestive enzyme located in the gastric juices of the stomach, essential for breaking down proteins into smaller peptides, which can then be absorbed in the intestines.

May 4, 2025 · In summary, pepsin is a crucial digestive enzyme and the prototypical aspartic protease. It operates efficiently under acidic conditions and plays a vital role in initiating protein …

Pepsin is a vital enzyme that plays a significant role in protein digestion, regulating gastric function and contributing to immune health. Its activation, mechanism of action, and clinical …